Phytophotodermatitis: a diagnosis to consider.

نویسندگان

  • Marta Machado
  • Rita Lacerda Vidal
  • Patrícia Cardoso
  • Sónia Coelho
چکیده

To cite: Machado M, Vidal RL, Cardoso P, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2015-213388 DESCRIPTION A 3-year-old boy presented with pigmented (brownish) macules on his hands (figure 1), left arm (figure 2) and face (figure 3). The lesions appeared days after the boy played with common rue and were best noticed after sun exposure. Topical treatment with methylprednisolone 0.1% cream led to complete resolution within 2 weeks. Rue (Ruta graveolens; Rutaceae family) is a common plant in the Iberian Peninsula. It is believed to protect against evil spells; it usually presents with yellow flowers and has an unpleasant odour (figure 4). Rue extracts are often used in ointments for treating strains and muscle pain. Rutaceae plants contain psoralens or furocoumarins, which trigger a phototoxic eruption when activated by exposure to ultraviolet A radiation after contact with unprotected skin. By binding to RNA and DNA, these activated psoralens induce inflammation and cell membrane damage. Immediate washing is recommended after skin contact with rue. Exposure to sunlight and moist conditions (bathing or swimming) should be avoided in the first 48–72 h after contact. Typically, the acute lesions present with irregular erythematous areas, and sometimes vesicles and bullae, with sharp demarcation between lesional and uninvolved skin, which can result in a burnlike wound. Pruritus may accompany but is not a

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عنوان ژورنال:
  • BMJ case reports

دوره 2015  شماره 

صفحات  -

تاریخ انتشار 2015